You can use PTZ cameras, but Sighthound Video does not provide direct access to the cameras pan, tilt and zoom functionality. You can use the camera software to control PTZ manually, though if the camera is on and recording in Sighthound Video you might generate clips of false alerts. Sighthound Video is designed to work only with fixed cameras, so as the camera moves it tends to make the software think that the background objects are moving rather than the camera. As soon as the camera stops moving, however, everything should start working again. If you want to avoid these issues, just turn off the cameras from the monitor screen when you move them, and then turn them on again after you're done. You can also rename the location of the camera if you want to save the different "scenes" under different names.